Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
نویسندگان
چکیده
منابع مشابه
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
A "switch" from oxidative phosphorylation (OXPHOS) to aerobic glycolysis is a hallmark of T cell activation and is thought to be required to meet the metabolic demands of proliferation. However, why proliferating cells adopt this less efficient metabolism, especially in an oxygen-replete environment, remains incompletely understood. We show here that aerobic glycolysis is specifically required ...
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ژورنال
عنوان ژورنال: Cell
سال: 2013
ISSN: 0092-8674
DOI: 10.1016/j.cell.2013.05.016